APJ's Yin-Yang Role in Cardiac Function (IMAGE)

Sanford Burnham Prebys

APJ's Yin-Yang Role in Cardiac Function

Caption

APJ's yin-yang role in cardiac function: the receptor APJ serves a dual function in heart health, depending on how it’s activated. While APJ enhances heart health upon binding the hormone apelin (green), APJ can also trigger heart enlargement and failure when it senses certain mechanical changes (red).

Credit

Sanford-Burnham Medical Research Institute

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