Not Only Skin Deep (IMAGE) University of Pennsylvania School of Medicine Caption This is a horizontal section through the basal layer of newborn mouse epidermis, stained for HDAC1 (green) and P63 (red). Nuclei are stained blue. HDAC1 and HDAC2 mediate the repressive functions of P63 in epidermal development. Credit Matthew LeBoeuf, University of Pennsylvania School of Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.