Unraveling a von Willebrand Factor molecule (VIDEO)
Caption
One end of vWF multimer was anchored on microfluidic channel. The molecule unraveled when 10,000 ul/hr flow was applied and folded back after flow was stopped. The unraveling process is reversible. The extensions of vWF was along flow direction which has a small angle with the horizontal direction in the video. The max length of the extension reaches ~6 um. The extension of molecules varies as molecular size of vWF were different.
Credit
Professors Xiaohui (Frank) Zhang, Alparslan Oztekin, Xuanhong Cheng and Edmund Webb III of Lehigh University
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License
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