Barcoded dopaminergic amacrine cell (DAC) in the mouse retina (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

Barcoded dopaminergic amacrine cell (DAC) in the mouse retina

Caption

Light-Seq enabled the isolation of the full transcriptome of a very rare type of cell, known as “dopaminergic amacrine cell” (DAC, magenta), by retrieving merely four to eight individually barcoded cells per cross-section. DACs are extremely hard-to-isolate, also because of their intricate connections to other cells in the retina that were differently barcoded using Light-Seq.

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Wyss Institute at Harvard University

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