The three-dimensional structure of PAPP-A (VIDEO)

Aarhus University

Caption

The complex between PAPP-A and STC2 is a large molecule, which consists of 3600 amino acids. The catalytic domain of PAPP-A is colored red, and STC2 is colored blue. The active site of the catalytic domain, which includes a bound zinc ion, is shown at a higher magnification. In the movie, the entire complex rotates to emphasize the cavity of the complex .

Credit

Claus Oxvig, Aarhus University

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Video may be used only to illustrate the research described in the accompanying release.

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