Reduced myelination in APOE4 brain (IMAGE) Picower Institute at MIT Caption Black gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4 Alzheimer's disease risk gene. Credit Tsai Laboratory/MIT Picower Institute Usage Restrictions with credit License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.