Close-ups of cell nuclei (IMAGE) Max-Planck-Gesellschaft Caption Close-ups of cell nuclei in a human cell culture: HMGB1 protein (green) is usually found throughout the nucleus (dotted line). Mutant HMGB1, shown on the right, preferentially localizes at the nucleolus (marked in magenta) and forms a solidified layer over it, which causes disease. Credit MPIMG/ Henri Niskanen Usage Restrictions Use of images is limited to editorial coverage of scientific topics relating to the activities of the Max Planck Society. Any kind of commercial use (including, in particular, the exploitation of images by means of sale or incorporation in image databases or image catalogues) as well as any promotional use/use for merchandise purposes, disclosure to third parties or granting of related rights to third parties is expressly not permitted. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.