Chemogenetic attenuation of cortical seizures. (IMAGE)
Caption
Administration of deschloroclozapine (DCZ) rapidly suppressed cortical seizures (high yellow bars) and body/head seizure movements (red ticks) within minutes. These results highlight the potential of chemogenetic therapies for treating severe cases of epilepsy.
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Takafumi Minamimoto from the National Institutes for Quantum Science and Technology, Japan
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