Figure 2 (image) Arizona State University Share Print E-Mail Caption Edge of discovery: The method allows precision tracking of cell edge changes over time, where i, ii, and iii correspond to the binding stages of a typical interaction between a small molecule and surface membrane protein: (i) Koff (II) Kon (III) Koff. The small molecule-receptor binding event, seen in ii, causes a distortion in the cell membrane shape, while iii denotes dissociation of the small molecule. Red and blue rectangles represent the region of interest for differential detection. Credit The Biodesign Institute at Arizona State University Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.