Suppression of the mRNA Turn-Over Leads to Necroptosis (image) Okinawa Institute of Science and Technology (OIST) Graduate University Share Print E-Mail Caption Intact CCR4-NOT complex (on the left) suppresses mRNAs encoding RIPK1 and RIPK3 proteins, thereby aiding cell survival. CNOT3-depleted cells (on the right) reveal increased expression and stability of these mRNAs. Credit OIST Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.