Degradation of Ucp1 mRNA in Fat Cells (video) Okinawa Institute of Science and Technology (OIST) Graduate University Share Print E-Mail Loading video... Caption The animation illustrates OIST's findings in obesity: the degradation of Ucp1 mRNA in fat cells is mediated by Tob and Cnot7, which are recruited by BRF1. The decrease in Ucp1 is one of the contributing factors to obesity in mice and humans. Credit Letizia Diamante, Juna Kurihara, flaticon Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.