Reduce the Use (image) Brown University Share Print E-Mail Caption In a small clinical trial, the drug topiramate reduced the amount marijuana users smoked (solid line) compared to placebo (dotted line). Both groups received MET counesling. Credit Robert Miranda Jr./Brown University Usage Restrictions with credit Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.