Figure 2: Increased Neural Excitability by Inhibition of NMDA Receptors (image) University of Tokyo Share Print E-Mail Caption The research group used genetically engineered mice that expressed a green fluorescent protein when neural activity increases to monitor brain activity. (Left) Low-level neural activity during sleep without inhibition of NMDA receptors, a type of ion-channel protein found on the membrane of neurons. (Right) One important discovery was that in contrast to conventional theory, inhibiting NMDA receptors directly evokes neural activity and brings about waking. Credit Copyright: Ueda lab. Usage Restrictions For purposes related to reporting of the current research. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.