Hydrogen-Bonding Pairing Helps Design Better Drugs to Neutralize Gut Bacterial Infections (image) Baylor College of Medicine Share Print E-Mail Caption IP6, the natural inhibitor or ligand of Clostridium difficile's toxin, binds weakly to the toxin. This results in the toxin remaining active (center figure). Changing a single atom in IP6 to form IP6(S) results in stronger binding to the toxin and its inactivation (left side figure). Credit T. Savidge (BCM); K. Prince (TCH) Usage Restrictions As per Creative Commons Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.