Zika's Effect on Neural Stem Cell Immune Response (image) Cell Press Share Print E-Mail Caption This graphical abstract shows the findings of Dang and Tiwari et al., that Zika virus (ZIKV) attenuates growth in cerebral organoids from human embryonic stem cells by targeting neural progenitors. ZIKV activates the TLR3-mediated innate immune response, leading to dysregulation of a network of genes involved in neurogenesis, axon guidance, apoptosis, and differentiation. Credit Dang and Tiwari et al./Cell Stem Cell 2015 Usage Restrictions Credit Required. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.