Figure 3: Baicalein inhibits the growth of AOM-DSS-induced colon tumors in mice and the model for baicalein activity in MutSα-proficient and MutSα-deficient cells. A, B, AOM-DSS was used to induce colon tumors in mice fed a control or baicalein-supplemented diet. The number of tumors (length > 2mm) in the colons of male mice (A) or female mice (B) was counted. C: Representative images of hematoxylin-eosin (H&E) staining of colon sections. The scale bar indicates 200 μm. Data in all panels are shown as mean ± S.E. *p < 0.05, versus control diet.