The response to CFTR-targeted drugs measured by swelling of intestinal organoids differs between subjects with cystic fibrosis. This material relates to a paper that appeared in the 22 June 2016, issue of Science Translational Medicine, published by AAAS. The paper, by Johanna Dekkers at University Medical Center Utrecht in Utrecht, Netherlands, and colleagues was titled, "Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis."
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