Combination Therapy/Boosting PARP Inhibitors (image) University of Maryland School of Medicine Share Print E-Mail Caption The goal of the therapy is to cause the protein PARP to be trapped longer at the site of DNA damage within a cancer cell. Microscopic images show a damaged breast cancer cell treated with either a PARP inhibitor or a DNMT inhibitor (left) and one treated with both agents (right). PARP (in yellow) at the damage site prevents the cell from repairing itself, causing it to die. Credit Johns Hopkins Kimmel Cancer Center Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.