Progesterone May Be Key to Preventing Recurrent Early Miscarriage (image) Yale University Share Print E-Mail Caption Cyclin E staining of the endometrium from a patient's with recurrent pregnancy loss. On the left her endometrial gland is markedly positive (the brown staining) for glandular nuclear cyclin E staining, which is abnormal and is associated with early recurrent pregnancy loss. On the right is cyclin E staining from the same patient after she was treated with vaginal progesterone suppositories. Her endometrial glands are now negative (no brown staining), which is a normal finding. After this successful treatment she went on to have a normal pregnancy. Credit Harvey J. Kliman, M.D., Yale School of Medicine Usage Restrictions Please credit: Harvey J. Kliman, M.D., Yale School of Medicine Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.