Neuroticism and Openness (image) University of Cambridge Share Print E-Mail Caption High levels of neuroticism are associated with increased thickness and reduced folding in some regions of the brain. Openness is associated with reduced thickness and an increase in folding. Credit Luca Passamonti Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.