Dark Zone (image) Osaka University Share Print E-Mail Caption Dark zone is lost and the germinal center is collapsed upon Foxo1 ablation. Foxo1 has also important roles in the light zone B cells, including antigen presentation to TFH cells and expression of dark zone program genes. Credit Osaka University Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.