Experimental Design to Study the Effect of Artificially Induced Brain Waves (image) Institute for Basic Science Share Print E-Mail Caption Mice were located in a cage and give a mild electric shock after hearing a noise (left). During the night an optogenetic method (center) was used in some of the mice to induce thalamic spindles artificially. The mice were divided into three groups: in the first group the spindle could form a triple rhythm (IN, red), in the second group the spindle was induced "out of sync" (OUT, green) and in the third group no stimulation was received (NoSTIM, black). The day after, the researchers checked if the mice remembered either the location or the noise (right). If the mice recall the incident, they freeze in fear. If the thalamic spindles were induced in phase with the slow oscillations (IN, red), then the mice were better at remembering the location. If the same noise was presented in a different location, all mice were equally good at remembering it. Credit IBS, graphics modified from freepik.com Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.