A Novel Role For A C-terminal Region (Amino Acids 2042 And 2061) That Regulates Fast Release (image) Max Planck Florida Institute for Neuroscience Share Print E-Mail Caption A, Cartoon depicting truncated regions in our CaV2.1 α1 deletion mutants including the binding sites for CaV β4, CASK, RBP, PXXP, RIM1/2 and Mint-1 along with the effects of C-terminal truncations on ICa. B, Averaged traces of RRP and total releasable pool measurements from mice expressing Cre + full transcript CaV2.1 rescue (grey), Δ2365-2368 (cyan), Δ2212-2368 (yellow), Δ2061-2368 (purple), Δ2042-2368 (green) or Δ2016-2368 (blue). ICa (top) and EPSCs (bottom) triggered by 3ms and 30ms pulses, plotted on top of each other (n=10 for each group, except for Δ2212-2368: n=8). Credit Max Planck Florida Institute for Neuroscience Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.