The video shows how the mice were trained to associate the blue light with a reward. The blue light gets turned off right after the mouse enters into the reward zone. Hungry mice are used for the food reward experiment and well-fed mice for WBS. WBS instills a dose of pleasure in a reward pathway of the brain via a headset implanted in the medial forebrain bundle. The video continues by showing the behavior of two trained mice in the same type of box. In the case of the food experiment, the impulse is driven by hunger, but in the WBS case, it is easier to mice to establish social rules. They define and respect their territory: one mouse receives the reward on the left and the other on the right zone of the box. They are also more tolerant to the mistakes of the other mice.
Il-Hwan Choe, Junweon Byun, Ko Keun Kim, Sol Park, Isaac Kim, Jaeseung Jeong, Hee-Sup Shin from Institute for Basic Science(IBS)