MRI showing focal restriction of diffusion (A, red arrows). Biopsy from a kidney allograft shows inflammatory cell infiltration typical for allograft infection (granulocytes (CD15, B), and T cells (CD3, C). Corresponding upregulated CXCR4 expression (D, white arrows). Additional markers of cell infiltration (B cells (CD20, E), and macrophages (CD68, F). Scale bar indicates 200 μm.
T Derlin et al., Hannover Medical School, Hannover, Germany