Degenerating Interneurons in Frontotemporal Lobar Degeneration (FTLD) Mice (image) Nagoya University Share Print E-Mail Caption (a) Poly-ubiquitin positive protein aggregates (arrows) in the hippocampus of aged FTLD mice (TDP-43 transgenic mice). (b) Immunofluorescence staining show these aggregates contain p62 and parvalbumin, a marker of interneurons (arrows). (c) Staining by parvalbumin antibody show intact (arrowheads) and degenerating interneurons (arrows) in the hippocampus of aged FTLD mice. Credit Hitomi Tsuiji and Koji Yamanaka Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.