Brain Sections of Alzheimer's Mice before (Left) and after (Right) Treatment with Nicotinamide Ribos (image)

Ecole Polytechnique Fédérale de Lausanne

Caption

Whole-brain hemisphere sections of Alzheimer's mice, the model APP/PSEN1, before and after treatment with the NAD+ booster Nicotinamide riboside (NR). The beta-amyloid plaque content in the brain of the APP/PSEN1 mice (left), clearly visible by Thioflavin S staining in green color and associated to brain damage during the disease, is reduced after 10 weeks treatment with NR (right).

Credit

Vincenzo Sorrentino, Mario Romani, Francesca Potenza/EPFL.

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