The Morphogenesis Process of a Mouse Kidney in Vivo and the Conventional Kidney Organoid From Plurip (image) Kumamoto University Share Print E-Mail Caption [Top] Between 8.75 and 11.5 days, the Wolffian duct in the mouse embryo matures and acquires branching capacity. After 11.5 days, nephron and interstitial progenitor cells, as well as the ureteric bud, start to develop. Branching of the ureteric bud and higher-order kidney structures form at around 15.5 days. [Bottom] Previously developed PSC-derived kidney organoids contained randomly induced nephron structures which lacked organization and inter-nephron connections. Note the lack of branched ureteric epithelium and nephron progenitors. Credit Dr. Atsuhiro Taguchi & Professor Ryuichi Nishinakamura Usage Restrictions This image may only be used in conjunction with the accompanying release, or stories written about the work described in the release with reference to the original work. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.