Interferon Illustration (image) Howard Hughes Medical Institute Share Print E-Mail Caption In a thick membrane that lines the uterus during pregnancy, cells infected with Zika (purple) secrete type I interferons (blue stars). Fetuses that lack protein receptors that bind interferons continue to develop (IFNAR-/- fetus, left). In contrast, fetuses with the receptors are disturbed by type I interferons, which disrupt the development of the placenta and lead to abnormal blood vessel growth, hypoxia, and fetal death (IFNAR +/-, right). Credit Akiko Iwasaki & Laura Yockey/ Yale/Howard Hughes Medical Institute Usage Restrictions Must use credit. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.