Developmental YAPdeltaC Rescues Adult Symptom of SCA1 (image) Tokyo Medical and Dental University Share Print E-Mail Caption Black bars indicate durations when YAPdeltaC was expressed. Pre-onset expression of YAPdeltaC, but not post-onset YAPdeltaC, elongates lifespan of SCA1 model mice. The recovery of motor function was also found in pre-onset but not post-onset expression of YAPdeltaC. These results indicate that developmental pathology regulates post-onset progression of the disease in SCA1. Credit Department of Neuropathology, TMDU Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.