Levers and Zippers in the Cell's 'Customs' (image) FECYT - Spanish Foundation for Science and Technology Share Print E-Mail Caption This is a representation of the two voltage coupling models in a potassium ion channel. Above, the canonical model: the voltage sensor (blue helix) acts as a lever that moves the linker (green segment), causing the turquoise helix in the lower part of the pore to adjust to open or close it. Bottom, the non-canonical coupling mechanism: the voltage sensor (blue helix) adjusts to an upper part of the pore (orange helix) like a zipper, which again impacts on the turquoise helix by affecting the pore state, opening it or closing it. Credit Fernández-Mariño et al./ WISC Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.