New Computational Tool Predicts Progression of Metabolic Syndrome in Mice (image) PLOS Share Print E-Mail Caption The study published by Rozendaal et al. makes use of a genetically modified animal model of which its metabolic system resembles that of the human. They have created a computational model that describes the major pathways in carbohydrate, fat and cholesterol metabolism. This model is graphically depicted in the block diagram that is displayed on top of the mouse. The arrows indicate transfer and exchange of different metabolites (denoted by the abbreviations in the boxes) between different tissues. Note that this model is also valid for the human metabolic system as well. Credit Rozendaal et al. Usage Restrictions CC-BY. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.