Reciprocal Regulation (image) Kanazawa University Share Print E-Mail Caption BAFF increased the IL-6-producing effector B cells but suppressed the IL-10-producing regulatory B cells. Furthermore, effector B cells play a pathogenic role in scleroderma while regulatory B cells play a protective role. Credit Kanazawa University Usage Restrictions The image may only be used with appropriate caption and credit. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.