M. Szczot and colleagues discovered that neurons in mice deficient in Piezo2 registered pinching stimuli (pink) but not gentle brushing stimuli (green), unlike neurons in control mice. This material relates to a paper that appeared in the Oct. 10, 2018, issue of Science Translational Medicine, published by AAAS. The paper, by S.E. Murthy at Howard Hughes Medical Institute in La Jolla, CA; and colleagues was titled, 'The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice.'
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