Long-term Prognosis of Chagas Patients Improved with Anti-parasite Drug (image) PLOS Share Print E-Mail Caption Unilateral painless periorbital swelling: "Romaña's Sign," associated with acute stage of Chagas disease. Credit Schmunis, CDC, 2007 (Public Domain) Usage Restrictions CC-BY: Redistribution permitted with credit. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.