Theoretical Mechanism (image) University of Pittsburgh Schools of the Health Sciences Share Print E-Mail Caption In young muscle, high levels of Klotho maintain mitochondia, which aids regeneration after injury. Age-related declines of Klotho lead to mitochondrial damage and impaired healing. Credit Sahu et al. (2018), Nature Communications Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.