Fungi and Crohn's (image)

Cell Press

Caption

This visual abstract depicts the findings of Limon et al., who surveyed intestinal wall associated fungi in patients with Crohn's disease (CD) and healthy controls and found a common commensal skin yeast called Malassezia, preferentially in CD patients. Malassezia exacerbates colitis in mouse models through mechanisms requiring CARD9, a signaling protein involved in anti-fungal immunity.

Credit

Limon et al.

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