Schematic Drawing of the Transmembrane Portion of TMEM16 Family Proteins (image) University of Groningen Share Print E-Mail Caption Schematic drawing of the transmembrane portion of TMEM16 family proteins. Upper panel shows a scramblase, in closed (nonconductive) intermediate (ion conduction) and open (lipid exchange) configuration. The lower panel shows an ion channel, which can only take on the closed and intermediate configuration. Credit C. Paulino, University of Groningen Usage Restrictions With credit Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.