Figure 1. (image)

Moscow Institute of Physics and Technology

Caption

Structures of GPCRs solved with stabilizing mutations predicted by CompoMug. (a) serotonin 5-HT2c receptor (PDB:), (b) frizzled FZD4 receptor, © prostaglandin EP3 receptor and (d) cannabinoid CB2 receptor. Stabilizing amino acid residues predicted with CompoMug are shown as sticks, with those mutations that were included into the final crystallized construct colored green.

Credit

Petr Popov et al./Current Opinion in Structural Biology

Usage Restrictions

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