Toomer et al. found that primary cilia (green), which serve as cellular antennae to receive signals from the extracellular space (grey) are required for cardiac valve development. Blue stained are cell nuclei. This material relates to a paper that appeared in the May 22, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by K. Toomer at Medical University of South Carolina in Charleston, SC; and colleagues was titled, 'Primary cilia defects causing mitral valve prolapse.'
Katelynn Toomer, Johns Hopkins postdoctoral Fellow; Russell Norris, Associate Professor of Medicine, the Medical University of South Carolina
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