Mice lacking the Dzip1 gene (right column) showed mitral valve prolapse and impaired formation of cilia (green) during development, compared to control animals (left column). This material relates to a paper that appeared in the May 22, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by K. Toomer at Medical University of South Carolina in Charleston, SC; and colleagues was titled, 'Primary cilia defects causing mitral valve prolapse.'
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