Can Deprescribing Drugs Linked to Cognitive Impairment Actually Reduce Risk of Dementia? (image) Regenstrief Institute Share Print E-Mail Caption Writing in JAMA Internal Medicine, Regenstrief Institute investigators Noll Campbell, Richard Holden and Malaz Boustani call for randomized deprescribing trials to address anticholinergic drug use as a potentially modifiable and reversible risk factor for dementia. The link between these drugs and cognitive impairment has been shown, they note, but is there a cause and effect relationship? Credit Regenstrief Institute Usage Restrictions Credit to Regenstrief Institute Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.