Using Single Cell RNA Sequencing, Mpg Researchers Create a Comprehensive Map of Human Liver Cells (image) Max Planck Institute of Immunobiology and Epigenetics Share Print E-Mail Caption Single cells were isolated from liver tissue derived from 9 different patients to perform single-cell RNA-sequencing. After applying computational single-cell analysis methods, a human liver cell atlas, or cell type map, was established, enabling the identification of previously unknown sub-types (depicted as clusters represented by numbers on the map). We discovered rare sub-types of bile duct cells in the liver, which include a population of liver epithelial progenitors that can give rise to organoids capable of developing into hepatocytes or bile duct cells. Credit MPI of Immunobiology and Epigenetics, Freiburg, Grün Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.