Nonribosomal Peptide Synthesase (video) Washington University in St. Louis Share Print E-Mail Loading video... Caption A multi-part enzyme called a nonribosomal peptide synthetase produces the highly reactive beta-lactone ring that is responsible for obafluorin's antimicrobial activity. Understanding how antibiotic scaffolds are constructed in nature can help scientists prospect for new classes of antibiotics through DNA sequencing and genome mining. For more information: doi.org/10.1038/s41467-019-11383-7 Credit Timothy Wencewicz, Washington University in St. Louis Usage Restrictions For editorial purposes Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.