AML Defective Blood Cells (image) Cold Spring Harbor Laboratory Share Print E-Mail Caption In AML, defective blood cells (stained purple) are present. When the cells have a double mutation of both the IDH2 and SRSF2 genes (bottom right), the number of defective cells rises considerably, indicating a more lethal disease. Credit Krainer lab/CSHL, 2019 Usage Restrictions Attribution needed Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.