Elomere Alterations in NF1-Solid Tumors (image) Johns Hopkins Medicine Share Print E-Mail Caption 'Telomere alterations in NF1-solid tumors. NF1-associated gliomas demonstrated telomeres of normal length (a), long (comparted to internal non-neoplastic cells, arrows) (b) or ALT (arrows) (c). ALT was relatively frequent in NF1-associated gliomas, and associated with a worse prognosis, while the majority of evaluable ALT negative gliomas had normal or abnormally long telomeres. In contrast, MPNST demonstrated telomeres of normal length (comparted to internal non-neoplastic cells, arrows) (d), short (comparted to internal non-neoplastic cells, arrows) (e) or ALT (arrows) (f). ' Credit Acta Neuropathologica Communications Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.