Here's Something that Will Raise Your Blood Pressure (image)
Caption
The apelin receptor (APJ) has been presumed to play an important role in the contraction of blood vessels involved in blood pressure regulation. A University of Tsukuba-led research team found that APJ was closely associated with hypertension through effects on vascular smooth muscle cells in laboratory mice. In addition, APJ worked synergistically with the α1A-adrenergic receptor to cause vasoconstriction. These results may help to understand blood pressure regulation and support therapies for vascular diseases.
Credit
The Japanese Biochemical Society
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