Survival curves in the KRAS, EGFR, and niche mutations cohorts. The red line represents the KRAS cohort, the purple line represents the EGFR cohort and the blue line represents the niche mutations cohort. The median survival times for the three cohorts are reported on the horizontal axis. The number of patients at risk at 0, 1, 2, 3, and 4 years from baseline is reported. Thick marks represent subjects lost to follow-up.