PAF15 (image) The Institute of Medical Science, The University of Tokyo Share Print E-Mail Caption PAF15 in a complex with PCNA undergoes UHRF1-mediated dual mono-ubiquitylation, which is essential for DNMT1 recruitment, and subsequent maintenance of DNA methylation. Credit © Atsuya Nishiyama Usage Restrictions The image may only be used with appropriate caption or credit. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.