Extension of healthspan extends lifespan. (A) Healthspan is the period of life without diseases. Diseases (black color) terminate lifespan. Subclinical aging (white color) progresses to pre-diseases (gray) and diseases (black). X axis: age. Y axis: loss of health (a sum of diseases) in log scale. (B) Longevity intervention slows aging and extends healthspan, automatically extending lifespan. (C) Unrealistic scenario "Healthspan without lifespan". Compressed morbidity (black). Either diseases progress instantly, or animals die from "health" rather than from diseases.
Mikhail V. Blagosklonny, email: Blagosklonny@oncotarget.com,
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